Which of the following factors is associated with the intrinsic pathway of coagulation?

The intrinsic pathway of coagulation is primarily associated with factors that activate one another within the blood, leading to the formation of a fibrin clot. Factors 12, 11, and 9 are integral to this pathway.

Factor 12, known as Hageman factor, is activated upon vascular injury and begins the intrinsic pathway. Once activated, it then activates factor 11. Activated factor 11 subsequently activates factor 9, which, along with factor 8, helps to activate factor 10 in the common pathway of coagulation. This cascade highlights the interconnectedness of these factors in promoting coagulation through the intrinsic pathway.

In contrast, other listed choices include factors that are either part of the extrinsic pathway (like factors 3 and 7) or the common pathway (such as factors 10 and 5, or 1 and 13). Understanding the roles and relationships of these coagulation factors is vital for comprehending hemostatic mechanisms in the body.