Which of the following adaptations occurs with an increase in temperature relating to the Bohr effect?

The correct adaptation that occurs with an increase in temperature relating to the Bohr effect is an increase in 2,3 DPG (2,3-diphosphoglycerate). An increase in temperature promotes the release of oxygen from hemoglobin, which facilitates oxygen delivery to tissues that are metabolically active and require more oxygen. In this context, 2,3 DPG plays an essential role as it binds to hemoglobin and stabilizes the deoxygenated form, further enhancing the release of oxygen.

As temperature rises, 2,3 DPG levels typically increase, which shifts the oxygen-hemoglobin dissociation curve to the right. This rightward shift means that hemoglobin has a decreased affinity for oxygen, allowing more oxygen to dissociate from hemoglobin and enter the tissues. This is particularly important during conditions like fever or in very active muscles, where more oxygen is needed.

Understanding this physiological mechanism illustrates the body's ability to adapt to increased metabolic demands and maintain effective oxygen delivery, particularly during exercise or thermal stress.